- ‘LigaChemBio Global R&D DAY 2025’ held on July 1
- Five 바카라 토토 사이트 assets in clinical trials, with 15 more advancing to clinical stage development
- CEO Kim Yong-zu: “Active development of novel target 바카라 토토 사이트s underway… New payloads are also in progress”

바카라 토토 사이트 Yong-zu, CEO of LigaChem Biosciences, delivers a speech at the LigaChemBio Global R&D DAY 2025 held on July 1. (Photo: Reporter Ji Yong Jun)
Kim Yong-zu, CEO of LigaChem Biosciences, delivers a speech at the LigaChemBio Global R&D DAY 2025 held on July 1. (Photo: Reporter Ji Yong Jun)

[by Ji, Yong Jun] “We aim to advance a total of 20 antibody-drug conjugate (ADC) assets into clinical trials by 2027.”

Kim Yong-zu, CEO of LigaChem Biosciences (hereinafter referred to as LCB), made this announcement during the ‘LigaChemBio Global R&D DAY 2025’ held on July 1 in Yeouido, Seoul. “We currently have five 바카라 토토 사이트 assets in clinical trials,” he further commented. “We are aggressively expanding our pipeline to ensure that an additional 15 바카라 토토 사이트 candidates enter clinical trials by 2027.”

Building upon its existing portfolio of 바카라 토토 사이트s utilizing small molecule compounds, LCB plans to advance the development of next-generation modalities, including ‘dual antibody 바카라 토토 사이트s,’ ‘immunomodulatory antibody conjugates (AICs),’ and ‘dual payload 바카라 토토 사이트s.’ The company also intends to explore the therapeutic potential of ‘peptide drug conjugates (PDCs).’ “Several of the 바카라 토토 사이트 candidates currently under development incorporate a significant portion of novel targets,” Kim noted.

LCB is also actively pursuing the development of novel payloads, with the objective of addressing resistance issues associated with currently used payloads in 바카라 토토 사이트s. At present, 바카라 토토 사이트 payloads are broadly categorized into two groups: those with high cytotoxicity, such as the ‘MMAE,’ ‘DM1,’ and ‘PBD’ series, and those with relatively low toxicity, such as the ‘Topo1’ series.

LCB introduced a series of new payload candidates, including TOPOi (non-camptothecins), immuno-oncology STING agonists (I-O STING), TLR7/8 agonists, novel payloads, and targeted protein degraders (TPD). “Identifying new payloads is a difficult task, but it is absolutely necessary,” Kim stated. “We intend to develop new payloads through open innovation in collaboration with external partners, rather than relying solely on internal development,” he added.

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