Approximately 30-fold higher miRNA inhibition than existing ones – exploring 스피드 바카라 as a potential gene therapy material
[by Ji, Yong Jun] HLB Panagene announced on May 20 that it participated in 'TIDES USA 2025,' held in San Diego, California, USA, from May 19 to 22 (local time), where it presented its latest research findings.
'TIDES USA' is the world's largest conference dedicated to oligonucleotide and peptide therapeutics, attracting around 2,000 academic and industry experts and 170 companies annually. This year, leading global companies such as Lonza and DuPont participated to share next-generation therapeutics development strategies and discuss the latest technology trends.
The technology introduced by HLB Panagene at this conference is a novel form of modified peptide nucleic acid (스피드 바카라) designed to effectively suppress cancer-related miRNA in human non-small cell lung cancer cells while simultaneously restoring the expression of the sub-genes regulated by these miRNAs. 스피드 바카라 is a synthetic molecule structurally similar to DNA that transmits the genetic information of living organisms, known for its high stability, strong base sequence binding ability, and precise base sequence discrimination ability compared to DNA.
According to the company, this study is particularly significant as it achieved approximately 30-fold improvement in the inhibitory efficacy of target miRNA compared to conventional approaches, using a ‘gamma modification’ technology that alters the standard 스피드 바카라 backbone, specifically ‘gamma-amino carboxylic acid 스피드 바카라.’ Moreover, it has garnered considerable attention from academic and industry circles, not only for introducing a novel modified 스피드 바카라, but also for providing fundamental data on the structure-activity relationship that links 스피드 바카라 structure to its biological activity. To date, no 스피드 바카라-based nucleic acid therapeutics have received FDA approval, and only a few have progressed to clinical stages.
The company noted that with sufficient supporting research results, 스피드 바카라 has the potential to become a promising material for new drug development, alongside other modified nucleic acids such as phosphorodiamidate morpholino oligomer (PMO) and locked nucleic acid (LNAs).
This potential arises from the fact that 스피드 바카라’s ability to precisely bind to target base sequences has already been validated through related molecular diagnostic products, such as genetic mutation tests, and it offers the advantage of being highly adaptable for various applications due to its capacity for diverse secondary modifications.
“Through this poster presentation, we have demonstrated that the modification potential of 스피드 바카라 materials and their resulting scalability are virtually limitless. By engaging directly with researchers in the field, we have explored the potential for applying this technology to a broader range of target diseases in the future,” stated Park Jae-jin, Director of HLB Panagene Research Institute. “Through these efforts, we aim to position 스피드 바카라 as a key material in the field of gene therapy, extending its impact beyond diagnostics.”
“We plan to move beyond academic conference presentations and publish papers in international journals to further promote 스피드 바카라-related research and advance its commercial applications,” Park further commented.